One of the times when I ran it I appear to have gotten a stack trace, but I'm not sure how helpful it will be:

Specified cast is not valid.

Server stack trace:
at Realisable.Utils.WcfExtensions.ExceptionMarshallingMessageInspector.System.ServiceModel.Dispatcher.IClientMessageInspector.AfterReceiveReply(Message& reply, Object correlationState)
at System.ServiceModel.Dispatcher.ImmutableClientRuntime.AfterReceiveReply(ProxyRpc& rpc)
at System.ServiceModel.Channels.ServiceChannel.HandleReply(ProxyOperationRuntime operation, ProxyRpc& rpc)
at System.ServiceModel.Channels.ServiceChannel.Call(String action, Boolean oneway, ProxyOperationRuntime operation, Object[] ins, Object[] outs, TimeSpan timeout)
at System.ServiceModel.Channels.ServiceChannel.Call(String action, Boolean oneway, ProxyOperationRuntime operation, Object[] ins, Object[] outs)
at System.ServiceModel.Channels.ServiceChannelProxy.InvokeService(IMethodCallMessage methodCall, ProxyOperationRuntime operation)
at System.ServiceModel.Channels.ServiceChannelProxy.Invoke(IMessage message)

Exception rethrown at [0]:
at System.Runtime.Remoting.Proxies.RealProxy.HandleReturnMessage(IMessage reqMsg, IMessage retMsg)
at System.Runtime.Remoting.Proxies.RealProxy.PrivateInvoke(MessageData& msgData, Int32 type)
at Realisable.Connectors.Service.IConnectorMetaPresenter.CreateMetaPresenter(String jobId, String hashCode, String systemId, ConnectorEssence connectorType)
at Realisable.Connectors.Service.PresenterClientProxy.c__DisplayClass9_0.b__0()
at Realisable.Connectors.Service.PresenterClientProxy.CreateMetaPresenter(String jobId, String hashCode, String systemId, ConnectorEssence connectorType)
at Realisable.IManWebUI.SystemConnectorTransform.LoadConnector(String systemId)
at Realisable.IManWebUI.SystemConnectorTransform.Refresh(Boolean updatingSystemDropDown, Boolean updatingViewDropDown)

And it looks like this populated into dstrace.log:

- System.InvalidCastException: Specified cast is not valid.
at Realisable.Utils.Converter.ConvertTo[T](String value)
at Realisable.Connectors.SageX3.SageX3Logon.Logon(SystemConnectorDTO system)
at Realisable.Connectors.SageX3.SageX3MetaDataExtender.OpenConnection(SystemConnectorDTO system)
at Realisable.Connectors.SageX3.SageX3MetaDataExtender.QueryWebServicesPublicationService(SystemConnectorDTO system)
at Realisable.Connectors.SageX3.SageX3MetaDataExtender.LoadMetaDocument(SystemConnectorDTO system)
at Realisable.Connectors.SageX3.SageX3MetaDataExtender.set_ConnectorSettings(SystemConnectorDTO value)
at Realisable.Connectors.CustomExtenderInterop.set_SystemId(String value)
at Realisable.Connectors.MetaDataPresenter..ctor(ConnectorEssence connectorEssence, String systemId)
at Realisable.Connectors.MetaPresenterFactory.CreateGetMetaPresenter(String jobId, String hashCode, String systemId, ConnectorEssence connectorType)
at Realisable.Connectors.MetaPresenterFactory.LoadMetaDataPresenter(String jobId, String hashCode, String systemId, ConnectorEssence connectorType)
at Realisable.DataService.ConnectorMetaPresenter.CreateMetaPresenter(String jobId, String hashCode, String systemId, ConnectorEssence connectorType)

I'm including a screenshot of the System Connector, I'm not sure if the error is due to something in our System Connector setup, or the X3 Web Service setup.

During a discussion about autoimmune disease, someone in my study group mentioned plasmapheresis as a treatment that works very differently from standard medications. I wanted to understand why doctors would use a procedure that removes plasma from the blood, so I read https://ways2well.com/blog/how-plasmapheresis-helps-autoimmune-conditions. The article helped me understand how plasmapheresis may reduce circulating antibodies, immune complexes, or other substances that can contribute to certain autoimmune problems. What I found especially useful was seeing where the procedure fits into treatment rather than thinking of it as a general therapy for every autoimmune condition. For me, it was a good overview of the mechanism, the kinds of situations where it may be considered, and the questions worth asking a specialist about risks, benefits, alternatives, and expected results.